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Splendare

Synthetic Chemistry Scientist

Medici Brands · New York, NY

On-siteEntry levelFull-time$90k–$110k/yr
Raised $271M in Aug 2026Posted Sep 16, 2026
Apply now ↗

Support bench-scale synthesis and process development of EPG, a structured lipid fat alternative. Run and optimize propoxylation and esterification reactions, troubleshoot performance, and generate data for scale-up and new SKU development, working closely with the R&D team.

What you'll do

  • Execute propoxylation and esterification reactions at bench scale
  • Troubleshoot yield, selectivity and byproduct issues and propose process changes
  • Prepare novel EPG analogs and intermediates for evaluation
  • Maintain detailed synthesis records and batch documentation
  • Collaborate with analytical scientists to interpret characterization data

Requirements

  • BS or MS in Organic Chemistry, Chemical Engineering, Polymer Chemistry, or related field
  • 1-3 years of hands-on synthetic chemistry lab experience
  • Experience running organic synthesis at bench scale, including setup, workup and purification
  • Familiarity with analytical techniques such as titration, GC, GPC
  • Comfortable working with reactive or hazardous reagents under safety protocols
  • Strong lab notebook and documentation practices
  • Ability to work independently and troubleshoot experiments in real time

Benefits

  • Salary inclusive of bonus
  • Company equity options
  • 100% covered health, vision and dental insurance
  • 401(k) with 4% match
  • Covered gym expenses
  • Substantial and required PTO

Skills

Differential Scanning CalorimetryGas ChromatographyGel Permeation ChromatographyLaboratory SafetyOrganic SynthesisTitration

Outlined skills are listed as required.

Full original description

Company:

Epogee is a food science and lipid chemistry company developing novel structured lipids for the food industry. Our flagship ingredient, EPG® (esterified propoxylated glycerol), is a patented fat alternative with 92% fewer calories than traditional fats. EPG can be used in a wide variety of food applications (e.g., frying and baking, as well as confectionery and snack applications). 

The Role:

Epogee is seeking an Associate Synthetic Chemistry Scientist to join our team supporting the synthesis and process development of EPG (esterified propoxylated glycerol) at bench-scale.  This is a hands-on role for someone who thrives on working in a laboratory environment.  You will have the opportunity to support the innovation of new EPG molecules by executing and optimizing propoxylation and esterification reactions, troubleshooting synthesis performance, and generating data needed to support process improvements, scale-up and new SKU development.  You’ll work closely with other members of the R&D team to translate results into actionable recommendations.

Key Responsibilities:

  • Follow safe handling procedures for reactive and hazardous reagents and maintain lab safety compliance to contribute to a culture of safety
  • Execute propoxylation and esterification reactions at bench scale, following and refining established synthesis protocols
  • Troubleshoot reaction performance issues (yield, selectivity, byproduct formation) and propose process modifications
  • Support raw material qualification and incoming feedstock testing for synthesis inputs
  • Assist with reaction monitoring to characterize reaction kinetics and inform process control strategies
  • Prepare novel EPG analogs or process intermediates for evaluation by the applications and analytical teams
  • Maintain detailed synthesis records, batch documentation, and safety data suitable for stage-gate review and technology transfer
  • Operate and maintain synthesis-related lab equipment (reactors, glassware, controlled-atmosphere/pressure systems)
  • Collaborate with analytical scientists to interpret characterization data (GPC, DSC, titration-based methods) and close the loop on synthesis optimization

Requirements

  • BS or MS in Organic Chemistry, Chemical Engineering, Polymer Chemistry, or a related field
  • 1–3 years of hands-on synthetic chemistry lab experience (industry or academic)
  • Practical experience running organic synthesis reactions at bench scale, including setup, workup, and purification
  • Familiarity with basic analytical techniques used to monitor reaction progress and product quality (e.g., titration, GC, GPC)
  • Comfortable working with reactive or hazardous reagents under appropriate safety protocols
  • Strong lab notebook and documentation practices
  • Ability to work independently and troubleshoot experimental issues in real time

Benefits

  • This is a full-time, in-office role based in New York City. We work onsite five days a week- when the culture fits, it is fun to be in the office together. 
  • Salary: $90,000 - $110,000 per year, inclusive of bonus. 
  • Company equity options. 
  • 100% covered Health, Vision, Dental Insurance.
  • 401(k) with 4% match.
  • Additional perks, such as covered gym expenses.
  • Substantial and required PTO.
  • Travel will be required to assess manufacturing operations. 

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